Antibiotic Filling and Sealing Machinery/Blow-Fill-Seal Medical Product Packaging Equipment with High Speed

After-sales Service: Field Installation, Commissioning and Training
Warranty: 1 Year
Type: Volumetric Filling Machine

Product Description

Overview & Basic Information
Automatic Grade
Automatic
Material Type
Granular
Filling Valve Head
Multi-Head
Dosing Device
Capacity Cup
Filling Principle
Pressure
Structure
Rotary
Packaging Material
Plastic (PE/PP)
Power Source
3p/AC380V
Installed Power
42kw
Manufacturing Standard
cGMP
Product Description
Volumetric BFS Machine Production Line/Blow-Fill-Seal Sterile Packaging Plant

The BFS is a dedicated state of the art system, enabling primary packaging of bulk pharmaceutical solutions into plastic containers of polypropylene or high density polyethylene or low density PE, using a Blow-Fill-Seal (BFS) technology. The BFS are performed automatically in a single machine under a controlled environment (sterile filtered air-shower).

Extrusion of plastic granulate into a parison at high temperatures
Blow-moulding of parison into a container with sterile-filtered air
Filling of sterile-filtered solution
Hermetic sealing of filled container
BFS Equipment 1
BFS Equipment 2

This Filling unit assembly is composed of filling nozzles, the manifold with filling valves, the assembly for sterile air shower around the nozzles, the guide bars and the drive. Special cylinder drives for shifting the nozzles up and down are available, ensuring a safe and clean assembly particularly suitable for clean environments.

BFS Component 1
BFS Component 2
Our Advantages
01 The design, MOC, manufacture, assembly and debugging of the BFS machine meet the requirements of the new GMP standards for production.
02 Advanced equipment with unique and reasonable structure, providing stable and reliable performance. Applicable for 0.2ml-1000ml plastic bottles.
03 Integrated bottle making, filling, and capping. The compact structure reduces clean workshop area and energy consumption.
04 Low-speed long-screw extruder driven by servo motor reduces thermal stress and accurately controls bottle preform size.
05 Automatic comparison and control with real-time feedback for every production cycle.
Advantage 1
Advantage 2
Advantage 3
Product Parameters
NO Project Parameters
1Size (L×W×H)3500*1400*2800mm
2Weight4.5T
3DeflasherInternal punching
4Power Source3P/AC380V
5Installed Power42Kw
6Power Rating30Kw
7Packing MaterialsPE/PP
8Specification1ml-50ml
9Capacity3000 pcs/h (1ml); 1500 pcs/h (10ml)
10Filling Accuracy±1.5% (based on 5ml)
11Manufacturing StandardcGMP
12Compress Airno oil, no water @ 8bar, 200NL/min
13Cooling Water8-12ºC @ 4bar, 2m³/h
14Pure Steam125ºC @ 2bar, 25kg/h
Production Environment & Quality Control
Production Environment
Workshop
Quality Assurance
Facility 1
Facility 2
Frequently Asked Questions
What is BFS technology?
Blow-Fill-Seal (BFS) technology is an automated manufacturing process where a container is formed, filled, and sealed in one continuous, sterile process.
What bottle sizes can this machine handle?
Our BFS machines can be customized to produce plastic containers ranging from 0.2ml to 1000ml, depending on specific user requirements.
Does the equipment meet international standards?
Yes, the design and manufacturing of the equipment comply with cGMP standards and IEC electrical safety requirements.
What are the primary materials used for the containers?
The machine primarily uses Polypropylene (PP), High-Density Polyethylene (HDPE), or Low-Density Polyethylene (LDPE).
What is the typical production capacity?
Capacity varies by bottle size; for example, it can reach up to 3000 pcs/hour for 1ml specifications and is customizable up to 18000 BPH.
How is filling accuracy maintained?
The machine features a high-precision filling system that maintains accuracy within ±1% to ±1.5% depending on the fill volume.

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